Long-Acting Injectables
ivisLab simulates drug release from real or synthetic depots using first-principles modeling, accelerating development of LAI's using microstructure science.
First-Principles Drug Release Modeling for Long-Acting Injectables
ivisLab enables scientists and researchers to perform in silico release simulations of long-acting injectable depots using detailed in-vitro or ex-vivo microstructure information. By leveraging advanced imaging technologies, ivisLab simulates drug release from actual depot structures formed post-injection—capturing the true complexity of formulation and injection dynamics.
Grounded in first-principles modeling, this approach reduces reliance on time-consuming and expensive in-vitro dissolution testing, accelerating development while improving mechanistic understanding of drug release behavior.
Enabling Rapid Prototyping Through First-Principles Simulation
Rooted in the principles of Quality by Design (QbD), ivisLab provides powerful tools that support rapid formulation prototyping and reduce reliance on traditional in-vitro testing. By generating synthetic implant microstructures and simulating drug release from first principles, ivisLab helps teams explore key formulation and injection parameters—de-risking product development and accelerating the path to optimized long-acting injectables.
Actionable Insights, Accelerated by Physics-Based Simulation
Whether using high-resolution microscopy data or simplified synthetic geometries, ivisLab delivers powerful, actionable insights into the performance of long-acting injectable formulations. By incorporating time-dependent polymer behavior, ivisLab captures the complex dynamics of real-world drug release from polymer-based systems.
Because these simulations are entirely in silico, results can be generated in minutes—potentially saving months of traditional in-vitro release testing and dramatically speeding up development cycles.
