dissoLab Particles

An in silico platform that models particle dissolution using size, shape, and microscopy images to enable predictive data-driven formulation decisions.

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dissoLab Particles

Tackle Dissolution Challenges Early with In-Silico Precision

Particle dissolution is a critical factor influencing product performance across a wide range of dosage forms. In particular, non-micronized particles in BCS Class II and IV compounds often present challenges due to dissolution rate limitations. dissoLab empowers formulators with a cutting-edge, fully in-silico platform for accurately modeling and characterizing particle dissolution behavior. By simulating performance based on hypothetical particle size distributions, dissoLab enables users to make informed formulation and manufacturing decisions—well before physical synthesis begins. This predictive capability not only accelerates development timelines by reducing reliance on physical release testing, but also supports smarter, data-driven strategies for product optimization from the earliest stages of development.

A plot showing the dissolution release of 4 different drug particle formulations.
dissoLab Particles

Unlock the Full Potential of Dissolution Modeling with dissoLab

Microstructure plays a critical role in product development and performance, particularly in particle dissolution, where two key factors govern the dissolution rate: particle size and particle shape. While advanced modeling techniques have begun to incorporate particle size distributions for improved accuracy, most still fall short in effectively addressing particle shape. dissoLab bridges this gap. Our cutting-edge platform is the first of its kind to simultaneously account for both size and shape distributions, delivering an industry-leading solution for accurately tracking particle surface evolution throughout the dissolution process.

Transform Your Program with Microstructure Science

Get started with a drug product digital twin.