Controlled Release Systems impact the health and well being of tens of millions of people every year. And yet, it is a relatively new field built both on solid fundamentals of chemistry and mass transport, as well as new discoveries in materials science and biology. It is also an interdisciplinary field and involves the convergence of a broad range of engineering, scientific, and medical disciplines.


Robert Langer, Sc. D.

DigiM developed a unique technology platform that takes controlled release system design and optimization to the next level.

Imaging

FIB-SEM
MicroCT/NanoCT
Representative drug sample strategy
In-line/On-line/At-line

Analytics

Advanced particle/void/dispersion quantification
Drug micro-structure/controlled release design evaluation

Simulation

Release performance prediction
Release mechanism determination
Release design optimization
 

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    Complete micro-characterization workflow

Two controlled release polymer film designs are evaluated. Their release performances are numerically compared to reveal the failure of one design.